The Significance and Role of Fibroscan Examination in the Management of Patients with Liver Diseases
Keywords:
FibroScan, transient elastography, liver fibrosis, liver cirrhosis, METAVIR system, shear wave elastography, LSM (Liver Stiffness Measurement), NAFLD, chronic hepatitis, noninvasive diagnostics, liver biopsy, hepatologyAbstract
This article investigated the diagnostic capabilities and clinical significance of FibroScan (transient elastography) technology in 320 patients with liver disease. During the study, the diagnostic utility of FibroScan in patients with chronic hepatitis B (n=98), chronic hepatitis C (n=87), nonalcoholic fatty liver disease The diagnostic accuracy of the FibroScan method was evaluated in patients with chronic hepatitis B (n=98), chronic hepatitis C (n=87), non-alcoholic fatty liver disease (NAFLD/NASH) (n=72), alcoholic liver disease (n=43), and other liver pathologies (n=20). According to the results, the overall diagnostic accuracy of the FibroScan method for determining stages of liver fibrosis was 91.1%, with a correlation coefficient of r=0.88 (p<0.001) compared to liver biopsy. The study proved that FibroScan is a worthy alternative to liver biopsy as a non-invasive method, reducing examination time by 76.5% and eliminating the risk of complications. The results indicated that the widespread implementation of FibroScan technology in Uzbekistan could fundamentally improve diagnostic quality in the fields of gastroenterology and hepatology.
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