Study of the Contemporary Microbial Landscape of Wounds of Various Localization

Tokhtamurod Ziyodulla Zikrilla; Bayjigitova Saodat  Alliyarovna

doi:10.51699/cajmns.v7i1.3064

Authors

Tokhtamurod Ziyodulla Zikrilla Associate Professor (PhD), Department of General Surgery, Tashkent State Medical University (Pediatric Campus), Uzbekistan
Bayjigitova Saodat Alliyarovna Assistant Professor at the Department of Surgical Diseases and Transplantology, Karakalpakstan Medical Institute, Uzbekistan

DOI:

https://doi.org/10.51699/cajmns.v7i1.3064

Keywords:

wound infection, microbiological analysis, wound exudate, opportunistic microflora

Abstract

The aim was to investigate the modern picture of micorbiocenosis in wounds of different localization and origin on the basis of microbiological control results over wound exudation for a long time period in patients with surgical pathology from comparison groups.A microbiological audit was undertaken over 5 years with a review of all cases involving 953 surgical patients. Wounds' microflora was qualitatively and quantitatively estimated by the use of routine bacteriological culture methods with bacteria cultivation on blood agar and selective media. The microbial contamination level was assessed by the Ryabinsky–Rodoman scale. The findings showed that an important diversity of wound microflora was observed according to wound location, origin and clinical context (eg: elective vs. emergency surgery). Gram-positive bacteria were implicated in most wound types as Staphylococcus aureus was the most prevalent pathogen. Enterobacteriaceae gram-negative bacteria were more prevalent in wounds with perineal location, diabetic foot and gangrenous process. A great number of wounds were sterile bacteriologically. The research represents the updated information on epidemiology in wound microflora and documentates a stubborn predominance of conditionally pathogenic microorganisms, as well shows the leading significance of Staphylococcus aureus for purulent- inflammatory processes. The findings emphasize the necessity of routine microbiological monitoring of wound infections to guide rational antimicrobial therapy and improve surgical outcomes. The study did not include molecular diagnostic techniques or antimicrobial resistance profiling, which should be addressed in future research.

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