Morphological Changes in Dilated Cardiomyopathy
DOI:
https://doi.org/10.51699/cajmns.v4i2.1386Keywords:
Heart, Cardiomyopathy, Dilated cardiomyopathy, Myocardium, Morphology, MicroscopyAbstract
At present, sudden cardiac death due to alcoholic cardiomyopathy is not only a difficult task for forensic medicine, but also an urgent medical and social problem [1-3]. The difficulty of diagnosing alcoholic cardiomyopathy under the guise of various forms of ischaemic heart disease does not always allow one to reach a unequivocal conclusion about the cause of death [4]. It is known that prolonged toxic effect of ethanol and its metabolites is expressed in deep depression of cellular energy metabolism and metabolic processes, leading to severe dystrophic and destructive changes in the main components of myocardial histohematic barrier (HIB), which in turn contributes to development of electrical instability of myocardium and sudden cardiac death [5, 6].
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